Aligning functional network constraint to evolutionary outcomes

Table 4 List of yeast genes that were found to adapt to novel environments, and were additionally shown to evolve these adaptations convergently across populations or species of yeast. Node hierarchy categories after discriminant function analysis (DFA) are shown in the first column. P - peripheral nodes, I - intermediate nodes

DFA estimated Node hierarchy	Gene symbol	ORF ID	Reference
I	STE11	YLR362W	Lang et al., 2013 [49]
I	STE12	YHR084W	Lang et al., 2013 [49]
I	STE4	YOR212W	Lang et al., 2013 [49]
P	KRE6	YPR159W	Lang et al., 2013 [49]
I	SFL1	YOR140W	Lang et al., 2013 [49]
I	STE5	YDR103W	Lang et al., 2013 [49]
P	ANP1	YEL036C	Lang et al., 2013 [49]
I	GCN1	YGL195W	Lang et al., 2013 [49]
I	ERG5	YMR015C	Gerstein et al., 2012 [50]
P	ERG7	YHR072W	Gerstein et al., 2012 [50]
I	CNE1	YAL058W	Lang et al., 2013 [49]
I	GPB1	YOR371C	Lang et al., 2013 [49]
P	KEG1	YFR042W	Lang et al., 2013 [49]
I	KRE5	YOR336W	Lang et al., 2013 [49]
I	TOH1	YJL171C	Lang et al., 2013 [49]
P	SUL4	YBR294W	Gresham et al. 2008 [51]
I	GAL3	YDR009W	Hittinger et al., 2004 [52] Stern, 2013 [38]
I	GIN4	YDR507C	Gresham et al. 2008 [51]
I	PDR1	YGL013C	Anderson et al. 2003 [53]
I	SGF73	YGL066W	Gresham et al. 2008 [51]
I	SET4	YJL105W	Lang et al., 2013 [49]
I	SIR1	YKR101W	Gresham et al. 2008 [51]
I	ACE2	YLR131C	Lang et al., 2013 [49]
I	GAS1	YMR307W	Lang et al., 2013 [49]
I	WHI2	YOR043W	Lang et al., 2013 [49]
I	CKA2	YOR061W	Gresham et al. 2008 [51]

ISSN: 2730-7182